Bio-identical hormones may be safer


Article on Bio-identical hormones printed in the Honolulu Advertiser December 31, 2009

Q: Lately I’ve been hearing a lot about bio-identical natural hormone replacement therapy for women. What is it? Is it safer than conventional hormones? And why would women want to take it?

For at least 20 years, naturopathic physicians have prescribed bio-identical natural hormones to help women with a number of different hormone imbalances. “Bio-identical” means that the chemical structure of the hormones is exactly like the hormones that women make in their own bodies; “natural” means that the hormones come from a natural source, such as a plant or an animal.

Many physicians now recommend bio-identical natural hormone replacement therapy (BHRT) rather than synthetic non-bio-identical hormones for a number of reasons. BHRT appears to be safer than synthetic non-bio-identical hormones such as those found in many prescription hormone regimes, including Provera and Premarin. (Premarin could be considered “natural” by some because it is derived from the urine of pregnant horses, but it is not bio-identical because it contains many different hormones – including horse hormones!). It is important to note that in 2002 the landmark hormone study called The Women’s Health Initiative was abruptly halted because it was found that Premarin and Provera increased the risk of breast cancer, heart disease, and strokes. In contrast, bio-identical hormones appear to be a much healthier option. According to a 2009 article by Kent Holtorf, MD, published in the journalPostgraduate Medicine, “Physiological data and clinical outcomes demonstrate that bio-identical hormones are associated with lower risks, including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animal-derived counterparts. Until evidence is found to the contrary, bio-identical hormones remain the preferred method of hormone replacement therapy. Further randomized controlled trials are needed to delineate these differences more clearly.”

Why would women want to take BHRT? As a naturopathic doctor specializing in women’s health, and with many of my patients going through mid-life changes associated with perimenopause, I can tell you that using very low-dose natural bio-identical hormones can enhance quality of life and improve libido. Natural hormones such as progesterone can also help women who suffer from PMS, heavy menstrual periods, and insomnia associated with low progesterone. Low-dose estrogen can help reduce midlife changes including hot flashes, night sweats, mood changes, and vaginal dryness. There are contraindications to using BHRT; for example, women who have had an estrogen- or progesterone-related cancer, or a history of blood clots, should not use any hormones. Every woman should be carefully evaluated by a doctor experienced in prescribing BHRT before beginning therapy, and she will need to have an annual pelvic exam, including a pap smear, and mammogram.


Dr. Laurie Steelsmith is a naturopathic physician and licensed acupuncturist in Honolulu, as well as author of the new book Natural Choices for Women’s Health, published by Random House. You can reach her and read her past columns at This column is for information only. Consult your health provider for medical advice.


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